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KMID : 0379119910190010079
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Korean Journal of Mycology
1991 Volume.19 No. 1 p.79 ~ p.84
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Production of Antihypertensive Constituents from Ganoderma lucidum IY005 by Fermentation Using Industrial Wastes
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김영일/Kim, Young Il
김병각/정훈/이권행/Kim, Byong Kak/Jeong, Hoon/Lee, Kweon Haeng
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Abstract
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Fruit bodies of Ganoderma lucidum have been used for most pharmacological studies, but pharmacological effects are likely variable because the habitats and strains of Ganoderma lucidum are different. Therefore, their fermentation is required to produce constant and reliable pharmacological constituents from Ganoderma lucidum. During the studies of medium for industrial application, it was found that ginseng root residues, remaining after being extracted with ethanol, were a good carbon source for a fermentation of Genoderma lucidum and a corn steep liquor was also economical for the nitrogen source. Yield of the mycelial cultured in ginseng root residues and corn steep liquor was 2.5 times higher than that in glucose and peptone, known as a conventional medium of Ganoderma lucidum. The polysaccharide content of the extracts from the cultured mycelia was higher than that from fruit bodies, but protein content was vice versa. Extracts of the cultured mycelia were more effective and lasting than extracts of the fruit bodies in decreased hypertention of spontaneously hypertensive rats (SHR).
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